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Details on Person Netrins are a family of extracellular proteins that include ...
| Class:Id | Summation:2447203 |
|---|---|
| _displayName | Netrins are a family of extracellular proteins that include ... |
| _timestamp | 2013-05-22 14:37:17 |
| created | [InstanceEdit:2447197] Jupe, S, 2012-08-13 |
| literatureReference | [LiteratureReference:2396418] Binding of netrin-4 to laminin short arms regulates basement membrane assembly [LiteratureReference:2426461] Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells |
| modified | [InstanceEdit:3597687] Jupe, S, 2013-05-22 |
| text | Netrins are a family of extracellular proteins that include axonal guidance factors. Their N-terminal domains are homologous to the LN domains of laminins. Netrin-4 (but not other forms) can bind laminin gamma-1 and gamma-3 short arms in basement membrane, suggesting a role in regulating basement membrane formation (Schneiders et al. 2007). Netrin-4 has been found associated in a functional complex with laminin gamma-1 chain and integrin alpha6beta1, suggesting a role in regulation of neurogenesis in the olfactory system (Staquicini et al. 2009). |
| (summation) | [Reaction:2447193] Ntn4 binds laminin-gamma-1 and -3 [Mus musculus] |
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No pathways have been reviewed or authored by Netrins are a family of extracellular proteins that include ... (2447203)
