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Details on Person UniProt:Q0P5A6 PSMD5
| Class:Id | ReferenceGeneProduct:244141 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Fri February 6 2015;chain:2-503 added on Fri February 6 2015;initiator methionine:1 for 244141 removed on Fri Nov 03 2023;initiator methionine: for 244141 added on Fri Nov 03 2023;initiator methionine: for 244141 removed on Fri Aug 15 2025;initiator methionine:1 for 244141 added on Fri Aug 15 2025 |
| _displayName | UniProt:Q0P5A6 PSMD5 |
| _timestamp | 2025-08-15 21:48:08 |
| chain | initiator methionine:1 chain:2-503 |
| checksum | 6C2ACAB4F222927B |
| comment | FUNCTION Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5 (By similarity).SUBUNIT Interacts with PSMC1, PSMC2, PSMD1 and PSMD6. Part of transient complex containing PSMD5, PSMC2, PSMC1 and PSMD2 formed during the assembly of the 26S proteasome (By similarity).DOMAIN Rich in dileucine repeats, which have been implicated in trafficking of a variety of transmembrane proteins.SIMILARITY Belongs to the proteasome subunit S5B/HSM3 family. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: 26S proteasome non-ATPase regulatory subunit 5 |
| geneName | PSMD5 |
| identifier | Q0P5A6 |
| isSequenceChanged | FALSE |
| keyword | Acetylation Chaperone Reference proteome |
| modified | [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9657908] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | PSMD5 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | PSMD5_BOVIN |
| sequenceLength | 503 |
| species | [Species:48898] Bos taurus |
| (referenceEntity) | [EntityWithAccessionedSequence:9909073] bPSMD5 [cytosol] [Bos taurus] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q0P5A6 PSMD5 (244141)
