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Details on Person UniProt:A1L390-2 PLEKHG3
| Class:Id | ReferenceIsoform:242989 |
|---|---|
| _chainChangeLog | chain:1-1219 added on Fri February 6 2015 |
| _displayName | UniProt:A1L390-2 PLEKHG3 |
| _timestamp | 2024-11-03 20:15:59 |
| chain | chain:1-1219 |
| checksum | DAEB5673340F4FBD |
| comment | FUNCTION Plays a role in controlling cell polarity and cell motility by selectively binding newly polymerized actin and activating RAC1 and CDC42 to enhance local actin polymerization.SUBCELLULAR LOCATION Colocalizes with actin at the leading edge of polarized cells.ALTERNATIVE PRODUCTS Intron retention. There are two regions of intron retention within the sequence which cause it to shift frame.SEQUENCE CAUTION Extended N-terminus. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: Pleckstrin homology domain-containing family G member 3 shortName evidence="9"PH domain-containing family G member 3 |
| geneName | PLEKHG3 KIAA0599 |
| identifier | A1L390 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Cytoplasm Cytoskeleton Methylation Phosphoprotein Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | PLEKHG3 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8962103] ENSEMBL:ENSG00000126822 PLEKHG3 [Homo sapiens] |
| secondaryIdentifier | PKHG3_HUMAN A1L389 B5MEC9 O60339 Q6GMS3 Q6P4B1 Q7L3S3 Q86SW7 Q8TEF5 Q96EW6 Q9BT82 |
| sequenceLength | 1219 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | A1L390-2 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:A1L390-2 PLEKHG3 (242989)
