Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Phosphorylation of PLC-gamma by p-BTK/p-SYK

Class:Id	Reaction:2424487
_displayName	Phosphorylation of PLC-gamma by p-BTK/p-SYK
_doRelease	TRUE
_timestamp	2017-11-29 21:34:17
authored	[InstanceEdit:2272794] Garapati, P V, 2012-05-25
catalystActivity	[CatalystActivity:2424478] protein tyrosine kinase activity of p-SYK/p-BTK [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2424489] Garapati, P V, 2012-07-23
edited	[InstanceEdit:2272794] Garapati, P V, 2012-05-25
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [Complex:2424457] p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:2685207] Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker [LiteratureReference:2424347] Btk is a positive regulator in the TREM-1/DAP12 signaling pathway
modified	[InstanceEdit:2428958] Garapati, P V, 2012-08-09 [InstanceEdit:2730898] Garapati, P V, 2012-12-05 [InstanceEdit:3145030] Garapati, P V, 2013-02-14 [InstanceEdit:9031492] Orlic-Milacic, Marija, 2017-11-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phosphorylation of PLC-gamma by p-BTK/p-SYK
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [Complex:2424467] p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:2424484] Phosphorylation of BTK by p-SYK [Homo sapiens] [Reaction:2424481] Recruitment of VAV and BTK to p-SLP-76 [Homo sapiens] [Reaction:2395412] Phosphorylation of SYK [Homo sapiens] [Reaction:2395412] Phosphorylation of SYK [Homo sapiens] [Reaction:210289] Recruitment of SYK to p-DAP12 [Homo sapiens]
releaseDate	2012-09-18
reviewed	[InstanceEdit:2428957] Lanier, Lewis L, 2012-08-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2464933] R-HSA-2424487.3
summation	[Summation:2424406] Three tyrosine residues at positions 771, 783 and 1254 in PL...
(hasEvent)	[Pathway:2424491] DAP12 signaling [Homo sapiens]
(precedingEvent)	[Reaction:2424485] Release of p-PLCG1 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9787712] Update Tracker - [Reaction:2424487] Phosphorylation of PLC-gamma by p-BTK/p-SYK - v44:[addLiteratureReference]
[Change default viewing format]

No pathways have been reviewed or authored by Phosphorylation of PLC-gamma by p-BTK/p-SYK (2424487)