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Details on Person UniProt:Q148I1 PAAF1
Class:Id
ReferenceGeneProduct:241519
_chainChangeLog
initiator methionine:1 added on Fri February 6 2015;chain:2-392 added on Fri February 6 2015;initiator methionine:1 for 241519 removed on Fri Nov 03 2023;initiator methionine: for 241519 added on Fri Nov 03 2023;initiator methionine: for 241519 removed on Fri Aug 15 2025;initiator methionine:1 for 241519 added on Fri Aug 15 2025
_displayName
UniProt:Q148I1 PAAF1
_timestamp
2025-08-15 21:32:31
chain
initiator methionine:1 chain:2-392
checksum
17174B16E81BB305
comment
FUNCTION Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Protects SUPT6H from proteasomal degradation (By similarity).SUBUNIT Interacts with PSMC1, PSMC2, PSMC3, PSMC4, PSMC5 and PSMC6. Interacts with SUPT6H.SIMILARITY Belongs to the WD repeat PAAF1/RPN14 family.
