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Details on Person PAPSe is reduced to SeO3(2-) by PAPSe reductase

Class:Id	Reaction:2408548
_displayName	PAPSe is reduced to SeO3(2-) by PAPSe reductase
_doRelease	TRUE
_timestamp	2015-11-20 15:07:37
authored	[InstanceEdit:5422928] Williams, MG, 2014-05-06
catalystActivity	[CatalystActivity:5359090] 3'-phosphoadenylylselenate reductase activity of PAPSeR [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2408534] Williams, MG, 2012-07-17
edited	[InstanceEdit:6793109] D'Eustachio, Peter, 2015-08-29
inferredFrom	[Reaction:2408518] PAPSe is reduced to SeO3(2-) by MET16 [Saccharomyces cerevisiae]
input	[SimpleEntity:5357722] PAPSe [cytosol] [SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:70106] H+ [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5359338] Sulphate metabolism of selenate-resistant Schizosaccharomyces pombe mutants
modified	[InstanceEdit:5359133] Williams, MG, 2014-04-08 [InstanceEdit:5422928] Williams, MG, 2014-05-06 [InstanceEdit:5422935] Williams, MG, 2014-05-06 [InstanceEdit:6793107] D'Eustachio, Peter, 2015-08-30 [InstanceEdit:6793354] D'Eustachio, Peter, 2015-09-01 [InstanceEdit:6804181] D'Eustachio, Peter, 2015-10-09 [InstanceEdit:6804182] D'Eustachio, Peter, 2015-10-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PAPSe is reduced to SeO3(2-) by PAPSe reductase
output	[SimpleEntity:5357720] SeO3(2-) [cytosol] [SimpleEntity:158466] PAP [cytosol] [SimpleEntity:29366] NADP+ [cytosol] [SimpleEntity:29356] H2O [cytosol]
precedingEvent	[Reaction:2408540] APSe is phosphorylated to PAPSe by PAPSS1,2 [Homo sapiens] [Reaction:2408525] H2SeO4 is converted to APSe by PAPSS1,2 [Homo sapiens]
releaseDate	2015-12-15
releaseStatus	NEW
reviewed	[InstanceEdit:6793106] Rush, MG, 2015-08-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6812318] R-HSA-2408548.2
summation	[Summation:5422889] A yet to be identified enzyme with 3'-phosphoadenylyl selena...
(hasEvent)	[Pathway:2408550] Metabolism of ingested H2SeO4 and H2SeO3 into H2Se [Homo sapiens]
(precedingEvent)	[Reaction:2408556] SeO3(2-) combines with GSH to form GSSeSG and GSSG [Homo sapiens] [Reaction:2408558] SeO3(2-) is reduced to H2Se by TXNRD1 [Homo sapiens]
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