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Details on Person SeO3(2-) is reduced to H2Se by TXNRD1

Class:Id	Reaction:2408527
_displayName	SeO3(2-) is reduced to H2Se by TXNRD1
_doRelease	TRUE
_timestamp	2015-11-20 15:07:26
authored	[InstanceEdit:5422928] Williams, MG, 2014-05-06
catalystActivity	[CatalystActivity:5359080] selenite reductase (NADPH) activity of 2xTXNRD1:2xFAD [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2408534] Williams, MG, 2012-07-17
edited	[InstanceEdit:6793109] D'Eustachio, Peter, 2015-08-29
input	[SimpleEntity:5357720] SeO3(2-) [cytosol] [SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5359340] Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non-stoichiometric oxidation of NADPH in the presence of oxygen
modified	[InstanceEdit:5333616] Williams, MG, 2014-02-19 [InstanceEdit:5357739] Williams, MG, 2014-03-26 [InstanceEdit:5359130] Williams, MG, 2014-04-08 [InstanceEdit:5359396] Williams, MG, 2014-04-09 [InstanceEdit:5422928] Williams, MG, 2014-05-06 [InstanceEdit:5422935] Williams, MG, 2014-05-06 [InstanceEdit:6793107] D'Eustachio, Peter, 2015-08-30 [InstanceEdit:6793354] D'Eustachio, Peter, 2015-09-01 [InstanceEdit:6804181] D'Eustachio, Peter, 2015-10-09 [InstanceEdit:6804182] D'Eustachio, Peter, 2015-10-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SeO3(2-) is reduced to H2Se by TXNRD1
output	[SimpleEntity:5357660] selanide [cytosol] [SimpleEntity:29366] NADP+ [cytosol] [SimpleEntity:29366] NADP+ [cytosol] [SimpleEntity:29366] NADP+ [cytosol] [SimpleEntity:29356] H2O [cytosol] [SimpleEntity:29356] H2O [cytosol] [SimpleEntity:29356] H2O [cytosol]
releaseDate	2015-12-15
releaseStatus	NEW
reviewed	[InstanceEdit:6793106] Rush, MG, 2015-08-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48898] Bos taurus
stableIdentifier	[StableIdentifier:6812300] R-BTA-2408527.2
summation	[Summation:5422865] In bovine cytosol, thioredoxin reductase 1 (TXNRD1) homodime...
(hasEvent)	[Pathway:2408516] Selenoamino acid synthesis and metabolism pathway - Inferred Events
(inferredFrom)	[Reaction:2408558] SeO3(2-) is reduced to H2Se by TXNRD1 [Homo sapiens]
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