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Details on Person Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation

Class:IdLiteratureReference:2408458
_displayNameMolecular basis of Tank-binding kinase 1 activation by transautophosphorylation
_timestamp2012-07-17 05:54:38
author[Person:2408456] Ma, Xiaolei
[Person:2408459] Helgason, Elizabeth
[Person:2408451] Phung, Qui T
[Person:2408452] Quan, Clifford L
[Person:2408454] Iyer, Rekha S
[Person:2408460] Lee, Michelle W
[Person:2399695] Bowman, Krista K
[Person:2408455] Starovasnik, Melissa A
[Person:2408457] Dueber, Erin C
created[InstanceEdit:2408453] Shamovsky, V, 2012-07-17
journalProc. Natl. Acad. Sci. U.S.A.
pages9378-83
pubMedIdentifier22619329
titleMolecular basis of Tank-binding kinase 1 activation by transautophosphorylation
volume109
year2012
(literatureReference)[CatalystActivityReference:9705331] protein serine/threonine kinase activity of dsRNA:RIG-I/MDA5:IPS-1:TRAF2/TRAF6:TANK:2xTBK1/IKKi [mitochondrial outer membrane] Crystal structure and mechanism of activation of TANK-binding kinase 1
[Summation:9705127] RIG‑I‑like receptors (RLRs) recognize RNAs from various RNA ...
[Summation:9705146] TBK1 (tumor necrosis factor (TNF) receptor-associated factor...
[Summation:9705310] Viral nucleic acids are sensed by cellular pattern-recogniti...
[Summation:9705332] Viral nucleic acids are sensed by cellular pattern-recogniti...
[Summation:9840615] Upon mitochondrial damage, TANK-binding kinase 1 (TBK1) is r...
[Reaction:2396002] TBK1 is phosphorylated within STING:TBK1:IRF3 complex [Homo sapiens]
[Reaction:3249390] TBK1 is phosphorylated within STING:TBK1:STAT6 complex [Homo sapiens]
[Reaction:9705137] TBK1 or IKBKE forms homodimers [Homo sapiens]
[Reaction:9705145] TBK1, IKBKE form homodimers [Homo sapiens]
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No pathways have been reviewed or authored by Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation (2408458)