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Details on Person First-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors

Class:IdLiteratureReference:2404237
_displayNameFirst-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors
_timestamp2012-07-16 19:10:57
author[Person:2404222] Yap, Timothy A
[Person:2404227] Yan, Li
[Person:2404228] Patnaik, Amita
[Person:2404218] Fearen, Ivy
[Person:2404225] Olmos, David
[Person:2404238] Papadopoulos, Kyriakos
[Person:2404240] Baird, Richard D
[Person:2404216] Delgado, Liliana
[Person:2404233] Taylor, Adekemi
[Person:2404220] Lupinacci, Lisa
[Person:2404212] Riisnaes, Ruth
[Person:2404219] Pope, Lorna L
[Person:2404231] Heaton, Simon P
[Person:2404211] Thomas, George
[Person:2404214] Garrett, Michelle D
[Person:2404242] Sullivan, Daniel M
[Person:2023302] de Bono, JS
[Person:2404215] Tolcher, Anthony W
created[InstanceEdit:2404229] Orlic-Milacic, M, 2012-07-16
journalJ. Clin. Oncol.
pages4688-95
pubMedIdentifier22025163
titleFirst-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors
volume29
year2011
(literatureReference)[Reaction:2400010] AKT inhibitors block AKT membrane recruitment [Homo sapiens]
[ChemicalDrug:2399927] MK2206 [cytosol]
[Summation:2404224] AKT inhibitors bind AKT and prevent its association with the...
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