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Details on Person Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

Class:IdLiteratureReference:2399826
_displayNameIdentification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
_timestamp2012-07-12 20:09:14
author[Person:2399857] Maira, Sauveur-Michel
[Person:2399876] Stauffer, Frédéric
[Person:2399809] Brueggen, Josef
[Person:2399770] Furet, Pascal
[Person:2399796] Schnell, Christian
[Person:2399745] Fritsch, Christine
[Person:2399775] Brachmann, Saskia
[Person:2399838] Chène, Patrick
[Person:2399769] De Pover, Alain
[Person:2399884] Schoemaker, Kevin
[Person:1678881] Fabbro, D
[Person:2399734] Gabriel, Daniela
[Person:2399814] Simonen, Marjo
[Person:2399862] Murphy, Leon
[Person:2399742] Finan, Peter
[Person:2399877] Sellers, William
[Person:2399763] García-Echeverría, Carlos
created[InstanceEdit:2399727] Orlic-Milacic, M, 2012-07-12
journalMol. Cancer Ther.
pages1851-63
pubMedIdentifier18606717
titleIdentification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
volume7
year2008
(literatureReference)[Reaction:2400009] PI3K inhibitors block PI3K catalytic activity [Homo sapiens]
[Reaction:9732513] PI3K inhibitors bind to Activator:PI3K [Homo sapiens]
[ChemicalDrug:2399744] BEZ235 [cytosol]
[CandidateSet:2399811] PI3K/mutant PI3K inhibitors [cytosol]
[CandidateSet:9732428] PI3K inhibitors [cytosol]
[Summation:2404213] A variety of inhibitors capable of blocking the phosphoinosi...
[Summation:9732467] A variety of inhibitors capable of blocking the phosphoinosi...
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No pathways have been reviewed or authored by Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity (2399826)