Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person BEZ235 [cytosol]

Class:IdChemicalDrug:2399744
_displayNameBEZ235 [cytosol]
_timestamp2018-12-12 00:29:43
compartment[Compartment:70101] cytosol
created[InstanceEdit:2399727] Orlic-Milacic, M, 2012-07-12
crossReference[DatabaseIdentifier:9628119] ChEBI:71952
disease[Disease:1500689] cancer
literatureReference[LiteratureReference:2399890] NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations
[LiteratureReference:2399826] Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
modified[InstanceEdit:2457718] Orlic-Milacic, M, 2012-08-28
[InstanceEdit:3004607] Orlic-Milacic, M, 2013-01-29
[InstanceEdit:9016686] Orlic-Milacic, Marija, 2017-08-14
[InstanceEdit:9028147] Weiser, JD
[InstanceEdit:9616752] Shorser, Solomon, 2018-08-13
[InstanceEdit:9619952] Wu, G, 2018-09-19
[InstanceEdit:9627975] Wu, G, 2018-11-05
[InstanceEdit:9631716] Wu, G, 2018-12-12
nameBEZ235
NVP-BEZ235
dactolisib
referenceEntity[ReferenceTherapeutic:9016662] dactolisib [Guide to Pharmacology:7950]
stableIdentifier[StableIdentifier:2465348] R-ALL-2399744.2
(hasMember)[CandidateSet:2399811] PI3K/mutant PI3K inhibitors [cytosol]
[CandidateSet:9732428] PI3K inhibitors [cytosol]
[Change default viewing format]
No pathways have been reviewed or authored by BEZ235 [cytosol] (2399744)
Follow Reactome