Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Similar to other PIK3R1 iSH2 domain mutations found in cance...
| Class:Id | Summation:2399712 |
|---|---|
| _displayName | Similar to other PIK3R1 iSH2 domain mutations found in cance... |
| _timestamp | 2012-07-12 16:15:45 |
| created | [InstanceEdit:2399709] Orlic-Milacic, M, 2012-07-12 |
| literatureReference | [LiteratureReference:2399688] Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation |
| text | Similar to other PIK3R1 iSH2 domain mutations found in cancer, substitution of arginine residue with threonine at position 574 of PIK3R1 is expected to relieve inhibitory effect on the catalytic subunit of PI3K, PIK3CA, resulting in constitutive activity of PI3K complex that contains PIK3R1 R574T mutant (Jaiswal et al. 2009). |
| (summation) | [EntityWithAccessionedSequence:2399540] PIK3R1 R574T [plasma membrane] [Homo sapiens] |
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No pathways have been reviewed or authored by Similar to other PIK3R1 iSH2 domain mutations found in cance... (2399712)
