Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Substitution of glutamine residue at position 546 of PIK3CA ...
| Class:Id | Summation:2399600 |
|---|---|
| _displayName | Substitution of glutamine residue at position 546 of PIK3CA ... |
| _timestamp | 2012-07-16 17:39:07 |
| created | [InstanceEdit:2399582] Orlic-Milacic, M, 2012-07-11 |
| literatureReference | [LiteratureReference:2399592] Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit |
| modified | [InstanceEdit:2404162] Orlic-Milacic, M, 2012-07-16 |
| text | Substitution of glutamine residue at position 546 of PIK3CA with lysine disrupts inhibitory interaction between the helical domain of PIK3CA and the nSH2 domain of PIK3R1. The PI3K complex containing PIK3CA Q546K mutant is constitutively active (Miled et al. 2007). |
| (summation) | [EntityWithAccessionedSequence:1500705] PIK3CA Q546K [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Substitution of glutamine residue at position 546 of PIK3CA ... (2399600)
