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Details on Person Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit

Class:Id	LiteratureReference:2399592
_displayName	Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit
_timestamp	2012-07-11 15:27:43
author	[Person:2399593] Miled, Nabil [Person:2399601] Yan, Ying [Person:2399597] Hon, Wai-Ching [Person:110609] Perisic, O [Person:2399591] Zvelebil, Marketa [Person:2399594] Inbar, Yuval [Person:2399589] Schneidman-Duhovny, Dina [Person:2399590] Wolfson, Haim J [Person:2399584] Backer, Jonathan M [Person:110612] Williams, RL
created	[InstanceEdit:2399582] Orlic-Milacic, M, 2012-07-11
journal	Science
pages	239-42
pubMedIdentifier	17626883
title	Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit
volume	317
year	2007
(literatureReference)	[Summation:2219521] Class IA PI3K is a heterodimer of a p85 regulatory subunit (... [Summation:2399583] Substitution of glutamic acid residue at position 542 of PIK... [Summation:2399585] Based on structural and functional studies of the PIK3CA E54... [Summation:2399586] Substitution of glutamic acid residue at position 545 of PIK... [Summation:2399595] Based on structural and functional studies of the PIK3CA E54... [Summation:2399598] Based on structural and functional studies of the PIK3CA E54... [Summation:2399599] Similar to PIK3CA E545K mutant (Miled et al. 2007, Huang et ... [Summation:2399600] Substitution of glutamine residue at position 546 of PIK3CA ... [Summation:2399602] Based on structural and functional studies of the PIK3CA E54... [Summation:2399611] Based on structural and functional studies of PIK3CA Q546K m... List all 35 refering instances
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