Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person PIK3R1 R574T [plasma membrane]

Class:IdEntityWithAccessionedSequence:2399540
_displayNamePIK3R1 R574T [plasma membrane]
_timestamp2014-09-26 07:14:40
compartment[Compartment:876] plasma membrane
created[InstanceEdit:2399539] Orlic-Milacic, M, 2012-07-10
crossReference[DatabaseIdentifier:2399537] COSMIC:COSV57128628
disease[Disease:1500689] cancer
[Disease:1500576] breast cancer
[Disease:1493885] bladder carcinoma
endCoordinate724
hasModifiedResidue[ReplacedResidue:2399538] L-arginine 574 replaced with L-threonine
literatureReference[LiteratureReference:2399688] Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation
modified[InstanceEdit:2399715] Orlic-Milacic, M, 2012-07-12
[InstanceEdit:2448601] Orlic-Milacic, M, 2012-08-13
[InstanceEdit:3662293] Orlic-Milacic, M, 2013-06-06
[InstanceEdit:5624358] Jupe, Steve, 2014-09-26
namePIK3R1 R574T
PIK3R1 Arg574Thr
referenceEntity[ReferenceGeneProduct:61192] UniProt:P27986 PIK3R1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2465050] R-HSA-2399540.1
startCoordinate1
summation[Summation:2399712] Similar to other PIK3R1 iSH2 domain mutations found in cance...
(hasCandidate)[CandidateSet:2399665] PIK3R1 iSH2 domain mutants [plasma membrane] [Homo sapiens]
(updatedInstance)[_UpdateTracker:9887669] Update Tracker - [EntityWithAccessionedSequence:2399540] PIK3R1 R574T [plasma membrane] - v46:[modifyName]
[Change default viewing format]
No pathways have been reviewed or authored by PIK3R1 R574T [plasma membrane] (2399540)