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Details on Person UniProt:Q9HB89 NMUR1

Class:IdReferenceGeneProduct:239772
_chainChangeLogchain:1-426 added on Sat February 7 2015
_displayNameUniProt:Q9HB89 NMUR1
_timestamp2026-02-20 22:13:05
chainchain:1-426
checksumF8DD781C020F04AA
commentFUNCTION Receptor for the neuromedin-U and neuromedin-S neuropeptides.SUBCELLULAR LOCATION Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.SIMILARITY Belongs to the G-protein coupled receptor 1 family.CAUTION It is uncertain whether Met-1 or Met-24 is the initiator.
created[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
descriptionrecommendedName: Neuromedin-U receptor 1 shortName: NMU-R1 alternativeName: G-protein coupled receptor 66 alternativeName: G-protein coupled receptor FM-3
geneNameNMUR1
GPR66
identifierQ9HB89
isSequenceChangedFALSE
keyword3D-structure
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Membrane
Proteomics identification
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9983091] Weiser, Joel, 2026-02-20
nameNMUR1
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8995568] ENSEMBL:ENSG00000171596 NMUR1 [Homo sapiens]
secondaryIdentifierNMUR1_HUMAN
O43664
Q7LDP6
Q8NE20
sequenceLength426
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:964790] NMUR1 [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q9HB89 NMUR1 (239772)