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Details on Person PIK3CA M1043V [cytosol]

Class:Id	EntityWithAccessionedSequence:2395932
_displayName	PIK3CA M1043V [cytosol]
_timestamp	2013-06-06 16:42:23
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2395937] Orlic-Milacic, M, 2012-07-06
crossReference	[DatabaseIdentifier:2395938] COSMIC:COSM30743 [DatabaseIdentifier:2395931] COSMIC:COSV55879858
disease	[Disease:1500689] cancer [Disease:2317358] endometrial cancer [Disease:1500576] breast cancer [Disease:1500575] ovarian cancer [Disease:2327997] pharynx cancer [Disease:2318576] oral cavity cancer [Disease:1248674] large intestine cancer [Disease:1248679] head and neck squamous cell carcinoma [Disease:1500699] lung cancer [Disease:1247632] glioblastoma
endCoordinate	1068
hasModifiedResidue	[ReplacedResidue:2395933] L-methionine 1043 replaced with L-valine
literatureReference	[LiteratureReference:2399562] The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations
modified	[InstanceEdit:2399648] Orlic-Milacic, M, 2012-07-11 [InstanceEdit:3662293] Orlic-Milacic, M, 2013-06-06
name	PIK3CA M1043V PIK3CA Met1043Val
referenceEntity	[ReferenceGeneProduct:61074] UniProt:P42336 PIK3CA [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2465045] R-HSA-2395932.1
startCoordinate	1
summation	[Summation:2399641] Substitution of methionine residue with valine at position 1...
(hasCandidate)	[CandidateSet:2399596] PIK3CA kinase domain mutants [cytosol] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9887550] Update Tracker - [EntityWithAccessionedSequence:2395932] PIK3CA M1043V [cytosol] - v46:[modifyName]
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No pathways have been reviewed or authored by PIK3CA M1043V [cytosol] (2395932)