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Details on Person A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1

Class:IdLiteratureReference:2395824
_displayNameA molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1
_timestamp2012-07-02 21:35:00
author[Person:2395847] Sakai, Yasunari
[Person:1427279] Furuichi, Masato
[Person:2395823] Takahashi, Masayuki
[Person:2395819] Mishima, Masaki
[Person:2395804] Iwai, Shigenori
[Person:2395834] Shirakawa, Masahiro
[Person:2395826] Nakabeppu, Yusaku
created[InstanceEdit:2395811] D'Eustachio, P, 2012-07-02
journalJ. Biol. Chem.
modified[InstanceEdit:2395857] D'Eustachio, P, 2012-07-02
pages8579-87
pubMedIdentifier11756418
titleA molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1
volume277
year2002
(literatureReference)[Reaction:2395818] NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP [Homo sapiens]
[CatalystActivityReference:9643113] 2-hydroxy-dATP hydrolase activity of NUDT1 [cytosol] The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein
[CatalystActivityReference:9643728] 2-hydroxy-ATP hydrolase activity of NUDT1 [cytosol] The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein
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