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Details on Person Hydroxyallysine and hydroxylysine can react forming the Schi...

Class:IdSummation:2395254
_displayNameHydroxyallysine and hydroxylysine can react forming the Schi...
_timestamp2012-07-10 13:26:51
created[InstanceEdit:2395344] Jupe, S, 2012-06-29
literatureReference[LiteratureReference:2245275] Mechanisms of maturation and ageing of collagen
modified[InstanceEdit:2399434] Jupe, S, 2012-07-10
textHydroxyallysine and hydroxylysine can react forming the Schiff base, which spontaneously undergoes an Amadori rearrangement resulting in the ketoimine cross-link hydroxylysino-5-ketonorleucine (HLKNL). This is much more stable than the aldimine crosslinks (Bailey et al. 1998).
(summation)[Reaction:2395302] Formation of hydroxylysino-5-ketonorleucine cross-links [Homo sapiens]
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