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Details on Person UniProt:Q8TBZ2 MYCBPAP
| Class:Id | ReferenceGeneProduct:238289 |
|---|---|
| _chainChangeLog | chain:1-947 added on Sat February 7 2015;chain:1-947 for 238289 removed on Mon Feb 26 2024;chain:1-984 for 238289 added on Mon Feb 26 2024 |
| _displayName | UniProt:Q8TBZ2 MYCBPAP |
| _timestamp | 2026-02-20 22:57:12 |
| chain | chain:1-984 |
| checksum | 6041ABAAC5E1A998 |
| comment | FUNCTION Plays a crucial role in centrosome-nuclear envelope docking during spermiogenesis, a key step for anchoring the centrosome to the nucleus that is essential for proper sperm flagellum biogenesis. Also required for acrosome biogenesis, manchette organization, and spermatid head morphogenesis, contributing to the complete and functional assembly of the sperm flagellum.SUBUNIT Interacts with CFAP65, CFAP70, CCP110 and ARMC3.SUBUNIT Interacts with MYCBP.INTERACTION Localizes in the sperm flagellum and central apparatus of the flagellar axoneme.SUBCELLULAR LOCATION Colocalizes with MYCBP in the cytoplasm,.ALTERNATIVE PRODUCTS Expressed specifically in testis.MISCELLANEOUS Gene prediction based on conservation.SEQUENCE CAUTION Extended N-terminus.SEQUENCE CAUTION Extended N-terminus. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: MYCBP-associated protein alternativeName: AMAM-1 alternativeName: AMY-1-binding protein 1 shortName: AMAP-1 |
| geneName | MYCBPAP AMAP1 |
| identifier | Q8TBZ2 |
| isSequenceChanged | FALSE |
| keyword | Alternative initiation Cell projection Cilium Cytoplasm Cytoplasmic vesicle Cytoskeleton Developmental protein Differentiation Flagellum Membrane Phosphoprotein Proteomics identification Reference proteome Spermatogenesis |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 [InstanceEdit:9909836] Weiser, Joel, 2024-05-14 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | MYCBPAP |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8991985] ENSEMBL:ENSG00000136449 MYCBPAP [Homo sapiens] |
| secondaryIdentifier | MYBPP_HUMAN A0A140VK87 A6NHJ3 B4DZQ1 Q8TDV8 Q9H0K0 |
| sequenceLength | 984 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:9862218] Unknown:Q8TBZ2-1 MYCBPAP [Homo sapiens] [ReferenceIsoform:9862219] Unknown:Q8TBZ2-2 MYCBPAP [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:9966856] MYCBPAP [cilium] [Homo sapiens] [EntityWithAccessionedSequence:9969468] MYCBPAP [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q8TBZ2 MYCBPAP (238289)
