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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person UniProt:Q9H069 DRC3

Class:IdReferenceGeneProduct:235646
_chainChangeLogchain:1-523 added on Fri February 6 2015
_displayNameUniProt:Q9H069 DRC3
_timestamp2026-02-20 23:04:47
chainchain:1-523
checksumB36DF1E42318D768
commentFUNCTION Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.SUBUNIT Component of the nexin-dynein regulatory complex (N-DRC). Interacts with DRC1 (PubMed:34169321). Interacts with DRC5 (By similarity). Interacts with DRC7 (By similarity).INTERACTION Belongs to the DRC3 family.
created[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
descriptionrecommendedName: Dynein regulatory complex subunit 3 alternativeName: Leucine-rich repeat-containing protein 48
geneNameDRC3
LRRC48
identifierQ9H069
isSequenceChangedFALSE
keyword3D-structure
Alternative splicing
Cell projection
Cilium
Coiled coil
Cytoplasm
Cytoskeleton
Flagellum
Leucine-rich repeat
Proteomics identification
Reference proteome
Repeat
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9841277] Weiser, Joel
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9862192] Weiser, Joel, 2024-02-26
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
[InstanceEdit:9983091] Weiser, Joel, 2026-02-20
nameDRC3
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9000019] ENSEMBL:ENSG00000171962 DRC3 [Homo sapiens]
secondaryIdentifierDRC3_HUMAN
A8KAE6
Q86SF9
Q86W73
Q8IWG0
sequenceLength523
species[Species:48887] Homo sapiens
(isoformParent)[ReferenceIsoform:235647] UniProt:Q9H069-2 DRC3 [Homo sapiens]
[ReferenceIsoform:414125] UniProt:Q9H069-1 DRC3 [Homo sapiens]
(referenceEntity)[EntityWithAccessionedSequence:9962982] DRC3 [cilium] [Homo sapiens]
[EntityWithAccessionedSequence:9969328] DRC3 [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q9H069 DRC3 (235646)