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Details on Person UniProt:Q8NI77 KIF18A
| Class:Id | ReferenceGeneProduct:234334 |
|---|---|
| _chainChangeLog | chain:1-898 added on Fri February 6 2015 |
| _displayName | UniProt:Q8NI77 KIF18A |
| _timestamp | 2024-11-03 20:01:31 |
| chain | chain:1-898 |
| checksum | 6DFD904378BF9B27 |
| comment | FUNCTION Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.SUBUNIT Interacts with CENPE and ESR1.INTERACTION By estrogen.PTM Glycosylated.PTM Ubiquitinated.SIMILARITY Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: Kinesin-like protein KIF18A alternativeName: Marrow stromal KIF18A shortName: MS-KIF18A |
| geneName | KIF18A OK/SW-cl.108 |
| identifier | Q8NI77 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure ATP-binding Cell projection Coiled coil Cytoplasm Cytoskeleton Glycoprotein Isopeptide bond Microtubule Motor protein Nucleotide-binding Nucleus Phosphoprotein Protein transport Proteomics identification Reference proteome Transport Ubl conjugation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | KIF18A |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8992528] ENSEMBL:ENSG00000121621 KIF18A [Homo sapiens] |
| secondaryIdentifier | KI18A_HUMAN Q4VPE3 Q86VS5 Q9H0F3 |
| sequenceLength | 898 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:376239] KIF18A [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q8NI77 KIF18A (234334)
