Query author contributions in Reactome
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Details on Person UniProt:Q9BUE6 ISCA1
| Class:Id | ReferenceGeneProduct:233068 |
|---|---|
| _chainChangeLog | transit peptide:1-12 added on Sat February 7 2015;chain:13-129 added on Sat February 7 2015 |
| _displayName | UniProt:Q9BUE6 ISCA1 |
| _timestamp | 2024-11-03 20:05:48 |
| chain | transit peptide:1-12 chain:13-129 |
| checksum | 2CA45D7821A62C43 |
| comment | FUNCTION Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly.SUBUNIT Interacts with CRY2, but not with CRY1 (in vitro).INTERACTION Detected in cerebellum, kidney and heart.DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the HesB/IscA family. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: Iron-sulfur cluster assembly 1 homolog, mitochondrial alternativeName: HESB-like domain-containing protein 2 alternativeName: Iron-sulfur assembly protein IscA shortName: hIscA |
| geneName | ISCA1 HBLD2 GK004 |
| identifier | Q9BUE6 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Disease variant Iron Iron-sulfur Metal-binding Mitochondrion Proteomics identification Reference proteome Transit peptide |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | ISCA1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9003005] ENSEMBL:ENSG00000135070 ISCA1 [Homo sapiens] |
| secondaryIdentifier | ISCA1_HUMAN B3KP34 B4DJI5 Q8ND75 Q9BZR2 |
| sequenceLength | 129 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8964829] UniProt:Q9BUE6-1 ISCA1 [Homo sapiens] [ReferenceIsoform:8964830] UniProt:Q9BUE6-2 ISCA1 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:5691212] ISCA1 [mitochondrial matrix] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9BUE6 ISCA1 (233068)
