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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person PIK3CA E542V [cytosol]

Class:IdEntityWithAccessionedSequence:2328074
_displayNamePIK3CA E542V [cytosol]
_timestamp2013-06-06 16:42:22
compartment[Compartment:70101] cytosol
created[InstanceEdit:2328075] Orlic-Milacic, M, 2012-06-22
crossReference[DatabaseIdentifier:2328076] COSMIC:COSV55881194
disease[Disease:1248674] large intestine cancer
[Disease:1500689] cancer
[Disease:1500576] breast cancer
[Disease:2317358] endometrial cancer
[Disease:1500575] ovarian cancer
endCoordinate1068
hasModifiedResidue[ReplacedResidue:2328077] L-glutamic acid 542 replaced with L-valine
literatureReference[LiteratureReference:2399592] Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit
modified[InstanceEdit:2399629] Orlic-Milacic, M, 2012-07-11
[InstanceEdit:3662293] Orlic-Milacic, M, 2013-06-06
namePIK3CA E542V
PIK3CA Glu542Val
referenceEntity[ReferenceGeneProduct:61074] UniProt:P42336 PIK3CA [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2465611] R-HSA-2328074.1
startCoordinate1
summation[Summation:2399616] Based on structural and functional studies of PIK3CA E542K m...
(hasCandidate)[CandidateSet:2399587] PIK3CA helical domain mutants [cytosol] [Homo sapiens]
(updatedInstance)[_UpdateTracker:9888522] Update Tracker - [EntityWithAccessionedSequence:2328074] PIK3CA E542V [cytosol] - v46:[modifyName]
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No pathways have been reviewed or authored by PIK3CA E542V [cytosol] (2328074)