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Details on Person Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1

Class:Id	Reaction:2327695
_displayName	Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1
_doRelease	TRUE
_timestamp	2013-09-05 11:51:30
authored	[InstanceEdit:2426629] Jupe, S, 2012-08-08
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:2327748] Jupe, S, 2012-06-21
edited	[InstanceEdit:4090280] Jupe, S, 2013-08-13
input	[DefinedSet:444996] Integrin alpha1beta1, alpha2beta1, alpha10beta1 [plasma membrane] [Homo sapiens] [DefinedSet:2424250] Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2327702] Interaction of type IV collagen with the isolated integrins alpha 1 beta 1 and alpha 2 beta 1 [LiteratureReference:2167979] Collagen XVI harbors an integrin alpha1 beta1 recognition site in its C-terminal domains [LiteratureReference:4084783] Selective binding of collagen subtypes by integrin alpha 1I, alpha 2I, and alpha 10I domains [LiteratureReference:4084771] The fibril-associated collagen IX provides a novel mechanism for cell adhesion to cartilaginous matrix [LiteratureReference:4084747] Platelet adhesion to collagen types I through VIII under conditions of stasis and flow is mediated by GPIa/IIa (alpha 2 beta 1-integrin)
modified	[InstanceEdit:2424251] Jupe, S, 2012-07-20 [InstanceEdit:2796108] Jupe, S, 2012-12-11 [InstanceEdit:2867907] Jupe, S, 2012-12-19 [InstanceEdit:4084921] Jupe, S, 2013-08-01 [InstanceEdit:4127405] Jupe, S, 2013-08-14 [InstanceEdit:4210796] Jupe, S, 2013-08-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1
output	[Complex:2424245] Collagen types III, IV, V, VI, VIII, IX, XVI:Integrins alpha1beta 1, alpha2beta1 [plasma membrane] [Homo sapiens]
releaseDate	2013-09-18
reviewed	[InstanceEdit:4088447] Ricard-Blum, Sylvie, 2013-08-13
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:4545297] R-HSA-2327695.2
summation	[Summation:2327767] The widely-expressed collagen receptors integrin alpha2beta1...
(hasEvent)	[Pathway:216083] Integrin cell surface interactions [Homo sapiens]
(normalReaction)	[Reaction:9018668] COL5A1-defective collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9864081] Update Tracker - [Reaction:2327695] Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 - v88:[modifyText]
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