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Details on Person UniProt:Q9NRV9 HEBP1

Class:IdReferenceGeneProduct:231639
_chainChangeLogchain:1-189 added on Sat February 7 2015
_displayNameUniProt:Q9NRV9 HEBP1
_timestamp2024-11-03 20:19:22
chainchain:1-189
checksum6ED12EA91B101B02
commentFUNCTION May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities.SUBUNIT Monomer.SUBCELLULAR LOCATION Forms a distorted beta-barrel structure, with two helices that are packed against the outer surface of the barrel. Porphyrins are expected to bind to a hydrophobic patch on the outer surface of the beta-barrel structure (By similarity).SIMILARITY Belongs to the HEBP family.
created[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
descriptionrecommendedName: Heme-binding protein 1 alternativeName: p22HBP
geneNameHEBP1
HBP
identifierQ9NRV9
isSequenceChangedFALSE
keywordCytoplasm
Proteomics identification
Reference proteome
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
nameHEBP1
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9002382] ENSEMBL:ENSG00000013583 HEBP1 [Homo sapiens]
secondaryIdentifierHEBP1_HUMAN
A8K1G2
Q9Y5Z5
sequenceLength189
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:444480] HEBP1 [extracellular region] [Homo sapiens]
(referenceSequence)[ModifiedResidue:444507] N-acetyl-L-methionine at 1
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No pathways have been reviewed or authored by UniProt:Q9NRV9 HEBP1 (231639)