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Details on Person UniProt:Q4G148 GXYLT1
| Class:Id | ReferenceGeneProduct:230565 |
|---|---|
| _chainChangeLog | chain:1-440 added on Sat February 7 2015 |
| _displayName | UniProt:Q4G148 GXYLT1 |
| _timestamp | 2025-02-21 19:59:39 |
| chain | chain:1-440 |
| checksum | 1A68504D913DBF0E |
| comment | FUNCTION Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.CATALYTIC ACTIVITY 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+)SUBCELLULAR LOCATION Belongs to the glycosyltransferase 8 family. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: Glucoside xylosyltransferase 1 ecNumber evidence="4"2.4.2.42 alternativeName: Glycosyltransferase 8 domain-containing protein 3 |
| geneName | GXYLT1 GLT8D3 |
| identifier | Q4G148 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Glycoprotein Glycosyltransferase Membrane Proteomics identification Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | GXYLT1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8962386] ENSEMBL:ENSG00000151233 GXYLT1 [Homo sapiens] |
| secondaryIdentifier | GXLT1_HUMAN B3KWJ2 Q8IXV1 Q96BH4 |
| sequenceLength | 440 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:230566] UniProt:Q4G148-2 GXYLT1 [Homo sapiens] [ReferenceIsoform:406862] UniProt:Q4G148-1 GXYLT1 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:1877988] GXYLT1 [Golgi membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q4G148 GXYLT1 (230565)
