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Details on Person PGH2 diffuses from the endoplasmic reticulum lumen to the cytosol

Class:Id	BlackBoxEvent:2299725
_displayName	PGH2 diffuses from the endoplasmic reticulum lumen to the cytosol
_doRelease	TRUE
_timestamp	2017-04-06 15:47:45
authored	[InstanceEdit:2299723] D'Eustachio, P, 2012-06-04
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:2299723] D'Eustachio, P, 2012-06-04
input	[SimpleEntity:30138] PGH2 [endoplasmic reticulum lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:8984390] The prostaglandin transporter PGT transports PGH(2)
modified	[InstanceEdit:2299728] D'Eustachio, P, 2012-06-04 [InstanceEdit:2303722] D'Eustachio, P, 2012-06-04 [InstanceEdit:2309789] D'Eustachio, P, 2012-06-05 [InstanceEdit:2569041] D'Eustachio, P, 2012-11-10 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8984457] Duenas, Corina, 2017-04-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PGH2 diffuses from the endoplasmic reticulum lumen to the cytosol
output	[SimpleEntity:265283] PGH2 [cytosol]
precedingEvent	[Reaction:140359] PGG2 is reduced to PGH2 by PTGS1 [Homo sapiens] [Reaction:140355] Arachidonate is oxidised to PGG2 by PTGS1 [Homo sapiens] [Reaction:2309773] PGG2 is reduced to PGH2 by PTGS2 [Homo sapiens] [Reaction:2309787] Arachidonate is oxidised to PGG2 by PTGS2 [Homo sapiens]
releaseDate	2012-12-04
reviewed	[InstanceEdit:2569042] Rush, MG, 2012-11-10
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3200454] R-HSA-2299725.4
summation	[Summation:2299727] PGH2 moves from the endoplasmic reticulum to the cytosol. Th...
(hasEvent)	[Pathway:2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX) [Homo sapiens]
(precedingEvent)	[Reaction:265295] Prostaglandin E synthase isomerizes PGH2 to PGE2 [Homo sapiens] [Reaction:2161549] PGH2 is reduced to PGF2a by AKR1C3 [Homo sapiens] [Reaction:2161612] PGH2 is reduced to PGF2a by FAM213B [Homo sapiens] [Reaction:2161660] PGH2 is isomerised to PGE2 by PTGES [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781505] Update Tracker - [BlackBoxEvent:2299725] PGH2 diffuses from the endoplasmic reticulum lumen to the cytosol - v61:[addLiteratureReference] [_UpdateTracker:9919390] Update Tracker - [BlackBoxEvent:2299725] PGH2 diffuses from the endoplasmic reticulum lumen to the cytosol - v90:[modifyText]
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