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Details on Person UniProt:Q70KY4 Foxo6
Class:Id
ReferenceGeneProduct:229833
_chainChangeLog
chain:1-559 added on Fri February 6 2015
_displayName
UniProt:Q70KY4 Foxo6
_timestamp
2023-11-03 17:59:53
chain
chain:1-559
checksum
A6FD814864572215
comment
FUNCTION Transcriptional activator.SUBCELLULAR LOCATION When phosphorylated, translocated from nucleus to cytoplasm. High nuclear localization after stimulation with growth factors.TISSUE SPECIFICITY Expressed in brain in areas of the nucleus accumbens, cingulate cortex, parts of the amygdala and in the hippocampus.DEVELOPMENTAL STAGE Expressed in developing brain in a specific temporal and spatial pattern.PTM Phosphorylation of Ser-184 is be important in regulating the transacriptional activity.