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Details on Person UniProt:Q70KY4 Foxo6

Class:IdReferenceGeneProduct:229833
_chainChangeLogchain:1-559 added on Fri February 6 2015
_displayNameUniProt:Q70KY4 Foxo6
_timestamp2023-11-03 17:59:53
chainchain:1-559
checksumA6FD814864572215
commentFUNCTION Transcriptional activator.SUBCELLULAR LOCATION When phosphorylated, translocated from nucleus to cytoplasm. High nuclear localization after stimulation with growth factors.TISSUE SPECIFICITY Expressed in brain in areas of the nucleus accumbens, cingulate cortex, parts of the amygdala and in the hippocampus.DEVELOPMENTAL STAGE Expressed in developing brain in a specific temporal and spatial pattern.PTM Phosphorylation of Ser-184 is be important in regulating the transacriptional activity.
created[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
descriptionrecommendedName: Forkhead box protein O6
geneNameFoxo6
identifierQ70KY4
isSequenceChangedFALSE
keywordActivator
Cytoplasm
DNA-binding
Nucleus
Phosphoprotein
Reference proteome
Transcription
Transcription regulation
modified[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameFoxo6
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierFOXO6_MOUSE
sequenceLength559
species[Species:48892] Mus musculus
(referenceEntity)[EntityWithAccessionedSequence:9615226] Foxo6 [nucleoplasm] [Mus musculus]
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No pathways have been reviewed or authored by UniProt:Q70KY4 Foxo6 (229833)