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Details on Person UniProt:Q3UYR4 Espnl
Class:Id
ReferenceGeneProduct:228537
_chainChangeLog
chain:1-1005 added on Fri February 6 2015
_displayName
UniProt:Q3UYR4 Espnl
_timestamp
2023-11-03 16:56:17
chain
chain:1-1005
checksum
2ADDE50A7AD8FC06
comment
FUNCTION Binds to but does not cross-link actin. Required for the formation and maintenance of inner ear hair cell stereocilia and staircase formation. Essential for normal hearing.SUBUNIT Interacts with MYO3A (via C-terminus). Interacts with MYO3B (via C-terminus).SUBCELLULAR LOCATION Expressed in inner ear hair cells (PubMed:25582750). Expressed in utricle hair bundles (at protein level). Expressed in choclea (at protein level) (PubMed:26926603).