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Query author contributions in Reactome

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Details on Person UniProt:Q8WWB3 DYDC1

Class:IdReferenceGeneProduct:227705
_chainChangeLogchain:1-177 added on Fri February 6 2015
_displayNameUniProt:Q8WWB3 DYDC1
_timestamp2024-11-03 19:51:01
chainchain:1-177
checksumFB3DA4290972C623
commentFUNCTION Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia (By similarity). Plays a crucial role during acrosome biogenesis (PubMed:19545932).SUBUNIT Component of the axonemal radial spoke complex 1 (RS1), at least composed of spoke head proteins RSPH1, RSPH3, RSPH9 and the cilia-specific component RSPH4A or sperm-specific component RSPH6A, spoke stalk proteins RSPH14, DNAJB13, DYDC1, ROPN1L and NME5, and the anchor protein IQUB (By similarity). Interacts with SH3GL3 (PubMed:19545932).INTERACTION Brain and testis. Accumulates during late stage of spermiogenesis.SIMILARITY Belongs to the dpy-30 family.CAUTION Sequence AAQ84766 was incorrectly indicated as originating from mouse.SEQUENCE CAUTION Intron retention.
created[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
descriptionrecommendedName: DPY30 domain-containing protein 1
geneNameDYDC1
DPY30D1
RSD-9
RSD9
identifierQ8WWB3
isSequenceChangedFALSE
keywordAlternative splicing
Cell projection
Cilium
Cytoplasm
Cytoskeleton
Flagellum
Proteomics identification
Reference proteome
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
nameDYDC1
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9000559] ENSEMBL:ENSG00000170788 DYDC1 [Homo sapiens]
secondaryIdentifierDYDC1_HUMAN
A8K927
Q5QP03
Q5QP04
Q6WNP4
Q6ZU87
sequenceLength177
species[Species:48887] Homo sapiens
(isoformParent)[ReferenceIsoform:8972787] UniProt:Q8WWB3-1 DYDC1 [Homo sapiens]
[ReferenceIsoform:8972788] UniProt:Q8WWB3-2 DYDC1 [Homo sapiens]
(referenceEntity)[EntityWithAccessionedSequence:9966768] DYDC1 [cilium] [Homo sapiens]
[EntityWithAccessionedSequence:9969354] DYDC1 [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q8WWB3 DYDC1 (227705)