THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE.
WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE
Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:Q9D6N5 Drap1
Class:Id
ReferenceGeneProduct:227556
_chainChangeLog
initiator methionine:1 added on Fri February 6 2015;chain:2-205 added on Fri February 6 2015
_displayName
UniProt:Q9D6N5 Drap1
_timestamp
2023-11-03 16:24:11
chain
chain:1-205
checksum
59CB729FFD7CB7CE
comment
FUNCTION The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).SUBUNIT Heterodimer with DR1. Binds BTAF1 (By similarity).SUBCELLULAR LOCATION Phosphorylation reduces DNA binding, but has no effect on heterodimerization and TBP binding.SIMILARITY Belongs to the NC2 alpha/DRAP1 family.
