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Details on Person UniProt:Q8NFW1 COL22A1
Class:Id
ReferenceGeneProduct:224914
_chainChangeLog
signal peptide:1-27 added on Fri February 6 2015;chain:28-1626 added on Fri February 6 2015
_displayName
UniProt:Q8NFW1 COL22A1
_timestamp
2024-08-09 18:41:37
chain
signal peptide:1-27 chain:28-1626
checksum
91018ABA2DD670EC
comment
FUNCTION Acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.SUBCELLULAR LOCATION Restrictive expression is observed at tissue junctions such as the myotendinous junction in skeletal and heart muscle, the articular cartilage-synovial fluid junction, or the border between the anagen hair follicle and the dermis in the skin. It is deposited in the basement membrane zone of the myotendinous junction and the hair follicle and associated with the extrafibrillar matrix in cartilage.SIMILARITY Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.