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Details on Person UniProt:Q96P44-2 COL21A1
| Class:Id | ReferenceIsoform:224911 |
|---|---|
| _chainChangeLog | signal peptide:1-22 added on Fri February 6 2015;chain:23-957 added on Fri February 6 2015 |
| _displayName | UniProt:Q96P44-2 COL21A1 |
| _timestamp | 2024-08-09 19:20:00 |
| chain | signal peptide:1-22 chain:23-957 |
| checksum | 4C5CDF5E6656A675 |
| comment | SUBCELLULAR LOCATION Found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.ALTERNATIVE PRODUCTS Highly expressed in lymph node, jejunum, pancreas, stomach, trachea, testis, uterus and placenta; moderately expressed in brain, colon, lung, prostate, spinal cord, salivary gland and vascular smooth-muscle cells and very weakly expressed in heart, liver, kidney, bone marrow, spleen, thymus, skeletal muscle, adrenal gland and peripheral leukocytes. Expression in heart was higher in the right ventricle and atrium than in the left ventricle and atrium.DEVELOPMENTAL STAGE Highest expression observed at the fetal stage. Expressed by smooth-muscle cells in the artery wall in a PDGF-dependent way.INDUCTION Stimulated by PDGF/platelet-derived growth factor.SIMILARITY Belongs to the fibril-associated collagens with interrupted helices (FACIT) family. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: Collagen alpha-1(XXI) chain |
| geneName | COL21A1 COL1AL FP633 |
| identifier | Q96P44 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Collagen Cytoplasm Extracellular matrix Glycoprotein Proteomics identification Reference proteome Repeat Secreted Signal |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 |
| name | COL21A1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8994149] ENSEMBL:ENSG00000124749 COL21A1 [Homo sapiens] |
| secondaryIdentifier | COLA1_HUMAN A6NIX5 B2R8J9 Q49A51 Q71RF4 Q8WXV8 Q9H0V3 |
| sequenceLength | 957 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | Q96P44-2 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q96P44-2 COL21A1 (224911)
