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Details on Person STAB1:ligand is endocytosed

Class:Id	BlackBoxEvent:2247513
_displayName	STAB1:ligand is endocytosed
_doRelease	TRUE
_timestamp	2014-02-06 22:16:10
authored	[InstanceEdit:3000476] May, B, 2013-01-26 [InstanceEdit:3222522] Neyen, Claudine, 2013-03-22
compartment	[Compartment:24337] endocytic vesicle membrane [Compartment:876] plasma membrane
created	[InstanceEdit:2247509] May, B, 2012-05-12
edited	[InstanceEdit:2230995] May, B, 2012-05-06
input	[Complex:2197764] STAB1:Ligand [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2213050] Role of liver sinusoidal endothelial cells and stabilins in elimination of oxidized low-density lipoproteins [LiteratureReference:2239377] Stabilin-1 localizes to endosomes and the trans-Golgi network in human macrophages and interacts with GGA adaptors [LiteratureReference:2197732] FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products [LiteratureReference:2213051] Rapid plasma membrane-endosomal trafficking of the lymph node sinus and high endothelial venule scavenger receptor/homing receptor stabilin-1 (FEEL-1/CLEVER-1) [LiteratureReference:3221877] Phosphatidylinositide 3-kinase activity is required for stabilin-1-mediated endosomal transport of acLDL [LiteratureReference:2197756] Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding
modified	[InstanceEdit:2512885] May, B, 2012-10-08 [InstanceEdit:3108241] May, B, 2013-02-10 [InstanceEdit:3166793] May, B, 2013-02-23 [InstanceEdit:3221958] May, B, 2013-03-17 [InstanceEdit:3222523] May, B, 2013-03-22 [InstanceEdit:3465590] May, B, 2013-05-17 [InstanceEdit:5258170] May, B, 2014-02-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	STAB1:ligand is endocytosed
output	[Complex:2247508] STAB1:Ligand [endocytic vesicle membrane] [Homo sapiens]
precedingEvent	[Reaction:2197770] STAB1 (FEEL-1) binds ligands [Homo sapiens]
releaseDate	2013-06-11
reviewed	[InstanceEdit:3222522] Neyen, Claudine, 2013-03-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3654411] R-HSA-2247513.2
summation	[Summation:2512838] The STAB1:ligand complex is endocytosed (Tamura et al. 2003,...
(hasEvent)	[Pathway:3000497] Scavenging by Class H Receptors [Homo sapiens]
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No pathways have been reviewed or authored by STAB1:ligand is endocytosed (2247513)