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Details on Person UniProt:O94779 CNTN5
| Class:Id | ReferenceGeneProduct:224716 |
|---|---|
| _chainChangeLog | signal peptide:1-18 added on Sat February 7 2015;chain:19-1072 added on Sat February 7 2015;propeptide:1073-1100 added on Sat February 7 2015 |
| _displayName | UniProt:O94779 CNTN5 |
| _timestamp | 2024-11-03 20:18:28 |
| chain | signal peptide:1-18 chain:19-1072 propeptide:1073-1100 |
| checksum | 5883575D84AD030E |
| comment | FUNCTION Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity).SUBUNIT Interacts with PTPRG.SUBCELLULAR LOCATION Expressed in brain and kidney and at very low level in placenta. Not expressed in other tissues. In brain, it is highly expressed in the occipital lobe, amygdala, cerebral cortex, frontal lobe, thalamus and temporal lobe. Expressed at moderate level in the cerebellum, substantia nigra, putamen, medulla and hippocampus. Weakly expressed in the spinal cord and caudate nucleus. Weakly or not expressed in the corpus callosum.SIMILARITY Belongs to the immunoglobulin superfamily. Contactin family.SEQUENCE CAUTION Truncated C-terminus. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: Contactin-5 alternativeName: Neural recognition molecule NB-2 shortName: hNB-2 |
| geneName | CNTN5 |
| identifier | O94779 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Cell adhesion Cell membrane Disulfide bond Glycoprotein GPI-anchor Immunoglobulin domain Lipoprotein Membrane Proteomics identification Reference proteome Repeat Signal |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | CNTN5 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9000523] ENSEMBL:ENSG00000149972 CNTN5 [Homo sapiens] |
| secondaryIdentifier | CNTN5_HUMAN A1L4P0 B7ZM07 E9PKE8 O94780 Q49AF3 |
| sequenceLength | 1100 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:224717] UniProt:O94779-2 CNTN5 [Homo sapiens] [ReferenceIsoform:402045] UniProt:O94779-1 CNTN5 [Homo sapiens] [ReferenceIsoform:8969129] UniProt:O94779-4 CNTN5 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:8940404] CNTN5 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:8940831] GPI-CNTN5 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:8941132] cleaved GPI-CNTN5 [extracellular region] [Homo sapiens] |
| (referenceSequence) | [GroupModifiedResidue:8940740] L-serine amide (GPI-anchor amidated amino acid carboxyl end residue(1−)) at 1072 [GroupModifiedResidue:8941120] L-serine amide (6-O-(2-aminoethylphosphono)-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-D-myo-inositol group) at 1072 |
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No pathways have been reviewed or authored by UniProt:O94779 CNTN5 (224716)
