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Details on Person UniProt:Q8BH15 Cnot10
Class:Id
ReferenceGeneProduct:224679
_chainChangeLog
initiator methionine:1 added on Fri February 6 2015;chain:2-744 added on Fri February 6 2015;initiator methionine:1 for 224679 removed on Fri Nov 03 2023;initiator methionine: for 224679 added on Fri Nov 03 2023;initiator methionine: for 224679 removed on Fri Aug 15 2025;initiator methionine:1 for 224679 added on Fri Aug 15 2025
_displayName
UniProt:Q8BH15 Cnot10
_timestamp
2025-08-15 22:07:01
chain
initiator methionine:1 chain:2-744
checksum
598C842BD70BC819
comment
FUNCTION Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex (By similarity).SUBUNIT Component of the CCR4-NOT complex; distinct complexes seem to exist that differ in the participation of probably mutually exclusive catalytic subunits. CNOT10 and CNOT11 form a subcomplex docked to the CNOT1 scaffold (By similarity).SUBCELLULAR LOCATION Belongs to the CNOT10 family.
