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Details on Person UniProt:Q6IPU0 CENPP

Class:IdReferenceGeneProduct:222858
_chainChangeLogchain:1-288 added on Fri February 6 2015
_displayNameUniProt:Q6IPU0 CENPP
_timestamp2024-11-03 19:40:19
chainchain:1-288
checksum19D32EF404E9EA7D
commentFUNCTION Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.SUBUNIT Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and CENPU.INTERACTION Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.ALTERNATIVE PRODUCTS Belongs to the CENP-P/CTF19 family.
created[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
descriptionrecommendedName: Centromere protein P shortName: CENP-P
geneNameCENPP
identifierQ6IPU0
isSequenceChangedFALSE
keyword3D-structure
Alternative splicing
Centromere
Chromosome
Coiled coil
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
nameCENPP
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8998799] ENSEMBL:ENSG00000188312 CENPP [Homo sapiens]
secondaryIdentifierCENPP_HUMAN
B3KRA5
B3KS17
Q5T9F8
Q5T9F9
sequenceLength288
species[Species:48887] Homo sapiens
(isoformParent)[ReferenceIsoform:8974202] UniProt:Q6IPU0-1 CENPP [Homo sapiens]
[ReferenceIsoform:8974203] UniProt:Q6IPU0-2 CENPP [Homo sapiens]
(referenceEntity)[EntityWithAccessionedSequence:375299] CENPP [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:606341] CENPP [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q6IPU0 CENPP (222858)