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Details on Person UniProt:Q8N0S6 CENPL
| Class:Id | ReferenceGeneProduct:222838 |
|---|---|
| _chainChangeLog | chain:1-344 added on Fri February 6 2015 |
| _displayName | UniProt:Q8N0S6 CENPL |
| _timestamp | 2024-11-03 19:55:36 |
| chain | chain:1-344 |
| checksum | 20EB5565F392FDE2 |
| comment | FUNCTION Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.SUBUNIT Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and CENPU.INTERACTION Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.ALTERNATIVE PRODUCTS Belongs to the CENP-L/IML3 family. |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: Centromere protein L shortName: CENP-L alternativeName: Interphase centromere complex protein 33 |
| geneName | CENPL C1orf155 ICEN33 |
| identifier | Q8N0S6 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Centromere Chromosome Nucleus Phosphoprotein Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | CENPL |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8990593] ENSEMBL:ENSG00000120334 CENPL [Homo sapiens] |
| secondaryIdentifier | CENPL_HUMAN Q5TEL5 Q96ND4 |
| sequenceLength | 344 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:222839] UniProt:Q8N0S6-2 CENPL [Homo sapiens] [ReferenceIsoform:222840] UniProt:Q8N0S6-3 CENPL [Homo sapiens] [ReferenceIsoform:411151] UniProt:Q8N0S6-1 CENPL [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:375295] CENPL [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:5633496] CENPL [nucleoplasm] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:Q8N0S6 CENPL (222838)
