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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person UniProt:Q8N801 STPG4

Class:IdReferenceGeneProduct:221502
_chainChangeLogchain:1-248 added on Sat February 7 2015
_displayNameUniProt:Q8N801 STPG4
_timestamp2025-08-15 22:17:33
chainchain:1-248
checksumF485CCA6A7BA3417
commentFUNCTION Maternal factor that plays a role in epigenetic chromatin reprogramming during early development of the zygote. Involved in the regulation of gametic DNA demethylation by inducing the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC).SUBUNIT Interacts with histone H3. Interacts with histone H4.INTERACTION Localizes in female and male zygote pronucleus. Associates preferentially with the paternal chromatin during zygote development.
created[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
descriptionrecommendedName: fullName evidence="3"Protein STPG4 alternativeName: fullName evidence="1"Gonad-specific expression gene protein shortName evidence="1"GSE alternativeName: fullName evidence="4"Sperm-tail PG-rich repeat-containing protein 4
geneNameSTPG4
C2orf61
identifierQ8N801
isSequenceChangedFALSE
keywordAlternative splicing
Chromatin regulator
Cytoplasm
Developmental protein
Nucleus
Proteomics identification
Reference proteome
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
nameSTPG4
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9002841] ENSEMBL:ENSG00000239605 STPG4 [Homo sapiens]
secondaryIdentifierSTPG4_HUMAN
H7C2Z2
sequenceLength248
species[Species:48887] Homo sapiens
(isoformParent)[ReferenceIsoform:8970893] UniProt:Q8N801-1 STPG4 [Homo sapiens]
[ReferenceIsoform:8970894] UniProt:Q8N801-2 STPG4 [Homo sapiens]
(referenceEntity)[EntityWithAccessionedSequence:9822589] STPG4 [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q8N801 STPG4 (221502)