Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Collagen VII triple-helices form an anti-parallel dimer, ass...

Class:IdSummation:2214317
_displayNameCollagen VII triple-helices form an anti-parallel dimer, ass...
_timestamp2012-04-30 16:02:40
created[InstanceEdit:2214325] Jupe, S, 2012-04-30
literatureReference[LiteratureReference:1643671] The tissue form of type VII collagen is an antiparallel dimer
[LiteratureReference:2214326] The carboxyl terminus of type VII collagen mediates antiparallel dimer formation and constitutes a new antigenic epitope for epidermolysis Bullosa acquisita autoantibodies
[LiteratureReference:1643684] Large complex globular domains of type VII procollagen contribute to the structure of anchoring fibrils
[LiteratureReference:2210345] Proteinases of the bone morphogenetic protein-1 family convert procollagen VII to mature anchoring fibril collagen
textCollagen VII triple-helices form an anti-parallel dimer, associating through disulfide bonds formed in a 60-nm overlap (NC2 domain) of the amino terminal triple helical ends. A portion of this region is proteolytically removed (Morris et al. 1986, Chen et al. 2001) prior to aggregation of dimers into anchoring fibrils (Lundstrum et al. 1986).
(summation)[Reaction:2214324] Collagen type VII dimerization [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Collagen VII triple-helices form an anti-parallel dimer, ass... (2214317)
Follow Reactome