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Details on Person Formation of MHC II alpha beta heterodimer

Class:Id	Reaction:2213239
_displayName	Formation of MHC II alpha beta heterodimer
_doRelease	TRUE
_timestamp	2024-05-16 16:17:30
authored	[InstanceEdit:2132294] Garapati, P V, 2012-02-21
compartment	[Compartment:5263265] lumenal side of endoplasmic reticulum membrane
created	[InstanceEdit:2213242] Garapati, P V, 2012-04-30
edited	[InstanceEdit:2132294] Garapati, P V, 2012-02-21
input	[DefinedSet:2130718] HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] [Homo sapiens] [DefinedSet:2130672] HLA II beta chain [lumenal side of endoplasmic reticulum membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2130633] Assembly of major histocompatibility complex class II subunits with invariant chain [LiteratureReference:2130674] The segment of invariant chain that is critical for association with major histocompatibility complex class II molecules contains the sequence of a peptide eluted from class II polypeptides [LiteratureReference:2130436] Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain [LiteratureReference:2130535] Interaction of MHC class II molecules with the invariant chain: role of the invariant chain (81-90) region
modified	[InstanceEdit:2213245] Garapati, P V, 2012-04-30 [InstanceEdit:2220950] Jupe, S, 2012-05-03 [InstanceEdit:2247929] Garapati, P V, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9910705] D'Eustachio, Peter, 2024-05-16
name	Formation of MHC II alpha beta heterodimer
output	[Complex:2213186] MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] [Homo sapiens]
releaseDate	2012-06-12
reviewed	[InstanceEdit:2247930] Neefjes, Jacques, 2012-05-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2295016] R-HSA-2213239.3
summation	[Summation:2213103] MHC II alpha and beta chains translocate to the ER and assoc...
(hasEvent)	[Pathway:2132295] MHC class II antigen presentation [Homo sapiens]
(precedingEvent)	[Reaction:2130478] Interaction of invariant chain trimer and MHC II alpha beta dimer [Homo sapiens] [Reaction:2213241] Formation of nonameric complex [Homo sapiens]
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No pathways have been reviewed or authored by Formation of MHC II alpha beta heterodimer (2213239)