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Details on Person TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome

Class:Id	Reaction:2213236
_displayName	TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome
_doRelease	TRUE
_timestamp	2012-05-31 09:42:11
authored	[InstanceEdit:2132294] Garapati, P V, 2012-02-21
compartment	[Compartment:17938] lysosomal membrane [Compartment:70101] cytosol [Compartment:263163] trans-Golgi network membrane
created	[InstanceEdit:2213242] Garapati, P V, 2012-04-30
edited	[InstanceEdit:2132294] Garapati, P V, 2012-02-21
input	[Complex:2213234] TGN-lysosome vesicle with nonameric complex [trans-Golgi network membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2130462] A role for acidic residues in di-leucine motif-based targeting to the endocytic pathway [LiteratureReference:2130726] Direct transport of newly synthesized HLA-DR from the trans-Golgi network to major histocompatibility complex class II containing compartments (MIICS) demonstrated using a novel tyrosine-sulfated chimera
modified	[InstanceEdit:2213245] Garapati, P V, 2012-04-30 [InstanceEdit:2247929] Garapati, P V, 2012-05-14 [InstanceEdit:2250299] Garapati, P V, 2012-05-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome
output	[Complex:167717] AP-1 Complex [cytosol] [Homo sapiens] [Complex:350827] Clathrin Triskelion [cytosol] [Homo sapiens] [Complex:2130532] Nonameric complex [lysosomal membrane] [Homo sapiens]
precedingEvent	[Reaction:2130641] Translocation of TGN-lysosome vesicle to lysosome [Homo sapiens] [BlackBoxEvent:2130619] TGN-lysosomal vesicle coat assembly [Homo sapiens]
releaseDate	2012-06-12
reviewed	[InstanceEdit:2247930] Neefjes, Jacques, 2012-05-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294843] R-HSA-2213236.2
summation	[Summation:2213098] On reaching the late endosomes/lysosomes the TGN-lysosome ve...
(hasEvent)	[Pathway:2132295] MHC class II antigen presentation [Homo sapiens]
(precedingEvent)	[Reaction:2130336] Initial proteolyis of Ii by aspartic proteases to lip22 [Homo sapiens]
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No pathways have been reviewed or authored by TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (2213236)