Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person The internalized nonameric complex passes through the endocy...
| Class:Id | Summation:2213096 |
|---|---|
| _displayName | The internalized nonameric complex passes through the endocy... |
| _timestamp | 2012-05-03 15:10:29 |
| created | [InstanceEdit:2213102] Garapati, P V, 2012-04-30 |
| literatureReference | [LiteratureReference:2130329] MHC II and the endocytic pathway: regulation by invariant chain |
| modified | [InstanceEdit:2220950] Jupe, S, 2012-05-03 |
| text | The internalized nonameric complex passes through the endocytic pathway and finally reach the acidic late endosomal/lysosomal compartments, where the Ii component is progressively degraded by proteases. Proteolysis of Ii occurs through sequential cleavages from the lumenal (C-terminal) side, generating cleavage products of approximately 22 kDa (lip22) and 10 kDa (lip10), finally leaving only CLIP bound within the peptide binding groove of MHC II (Landsverk et al. 2009). |
| (summation) | [BlackBoxEvent:2213235] Trafficking of nonameric complex in the endocytic pathway [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The internalized nonameric complex passes through the endocy... (2213096)
