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Details on Person UniProt:Q8NFZ8 CADM4

Class:IdReferenceGeneProduct:221178
_chainChangeLogsignal peptide:1-20 added on Sat February 7 2015;chain:21-388 added on Sat February 7 2015
_displayNameUniProt:Q8NFZ8 CADM4
_timestamp2024-11-03 20:18:12
chainsignal peptide:1-20
chain:21-388
checksumB22301C9E21A9339
commentFUNCTION Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.SUBUNIT Monomer and homodimer.INTERACTION Expressed in brain, prostate, brain, kidney and some other organs.PTM N-glycosylated.SIMILARITY Belongs to the nectin family.
created[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
descriptionrecommendedName: Cell adhesion molecule 4 alternativeName: Immunoglobulin superfamily member 4C shortName: IgSF4C alternativeName: Nectin-like protein 4 shortName: NECL-4 alternativeName: TSLC1-like protein 2
geneNameCADM4
IGSF4C
NECL4
TSLL2
identifierQ8NFZ8
isSequenceChangedFALSE
keywordCell adhesion
Disulfide bond
Glycoprotein
Immunoglobulin domain
Membrane
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Signal
Transmembrane
Transmembrane helix
Tumor suppressor
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
nameCADM4
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8957961] ENSEMBL:ENSG00000105767 CADM4 [Homo sapiens]
secondaryIdentifierCADM4_HUMAN
B2R7L5
Q9Y4A4
sequenceLength388
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:8958376] CADM4 [extracellular region] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q8NFZ8 CADM4 (221178)