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Details on Person activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane]

Class:IdComplex:2201325
_displayNameactivated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane]
_timestamp2018-08-09 02:31:25
compartment[Compartment:876] plasma membrane
created[InstanceEdit:2201327] Shamovsky, V, 2012-04-19
hasComponent
literatureReference[LiteratureReference:2201318] MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction
modified[InstanceEdit:2206276] Shamovsky, V, 2012-04-26
[InstanceEdit:2299707] Shamovsky, V, 2012-06-01
[InstanceEdit:2428907] Shamovsky, V, 2012-08-08
[InstanceEdit:5365826] Shamovsky, V, 2014-04-24
[InstanceEdit:5368324] Shamovsky, V, 2014-04-28
[InstanceEdit:8959586] Weiser, JD
[InstanceEdit:9615894] Shamovsky, Veronica, 2018-08-09
nameactivated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK
activated TLR2/4:p-4Y-MAL:PI(4,5)P2:BTK
relatedSpecies[Species:181384] Chlamydia trachomatis
[Species:180800] Neisseria meningitidis serogroup B
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2299182] R-HSA-2201325.3
(hasComponent)[Complex:166062] MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] [Homo sapiens]
[Complex:937033] oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] [Homo sapiens]
[Complex:9037685] MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane] [Homo sapiens]
(input)[Reaction:166072] MyD88 forms a complex with TIRAP:activated TLR2/4 [Homo sapiens]
[FailedReaction:5602606] Defective MyD88 does not bind MAL(TIRAP):TLR2/4 [Homo sapiens]
(output)[Reaction:2201322] TIRAP is phosphorylated by BTK [Homo sapiens]
(updatedInstance)[_UpdateTracker:9873038] Update Tracker - [Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] - v42:[addLiteratureReference, modifyName, updateContainedComponent]
[_UpdateTracker:9873527] Update Tracker - [Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] - v43:[updateContainedComponent]
[_UpdateTracker:9889729] Update Tracker - [Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] - v49:[add_removeHasComponent, modifyName, updateContainedComponent]
[_UpdateTracker:9890421] Update Tracker - [Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] - v52:[updateContainedComponent]
[_UpdateTracker:9893001] Update Tracker - [Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] - v54:[updateContainedComponent]
[_UpdateTracker:9895406] Update Tracker - [Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] - v59:[updateContainedComponent]
[_UpdateTracker:9896464] Update Tracker - [Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] - v60:[removeSpecies, updateContainedComponent]
[_UpdateTracker:9899548] Update Tracker - [Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] - v66:[addName]
[_UpdateTracker:9899735] Update Tracker - [Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] - v67:[updateContainedComponent]
[_UpdateTracker:9902093] Update Tracker - [Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] - v76:[updateContainedComponent]
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No pathways have been reviewed or authored by activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (2201325)
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