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Details on Person Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4

Class:IdLiteratureReference:2201278
_displayNameBruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4
_timestamp2012-04-19 19:56:44
author[Person:2201297] Jefferies, CA
[Person:2201315] Doyle, S
[Person:2201286] Brunner, C
[Person:2201313] Dunne, A
[Person:2201298] Brint, E
[Person:2201292] Wietek, C
[Person:2201310] Walch, E
[Person:2201281] Wirth, T
[Person:188072] O'Neill, LA
created[InstanceEdit:2201290] Shamovsky, V, 2012-04-19
journalJ Biol Chem
pages26258-64
pubMedIdentifier12724322
titleBruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4
volume278
year2003
(literatureReference)[Reaction:2201322] TIRAP is phosphorylated by BTK [Homo sapiens]
[Reaction:2559414] Activated TLR2/4:TIRAP interacts with BTK [Homo sapiens]
[Reaction:9696673] BTK binds MyD88 within the complex of TLR7, 8, 9:MyD88 dimer [Homo sapiens]
[Complex:2201331] TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] [Homo sapiens]
[Summation:2201324] Upon activation of TLR2/or 4 signaling pathway TIRAP (MAL), ...
[Summation:2559413] Bruton's tyrosine kinase (BTK) is a cytoplasmic protein tyro...
[Summation:9696666] Bruton’s tyrosine kinase (BTK) belongs to the Tec family of ...
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