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Details on Person UniProt:Q6UXY1-2 BAIAP2L2
| Class:Id | ReferenceIsoform:220110 |
|---|---|
| _chainChangeLog | chain:1-529 added on Sat February 7 2015 |
| _displayName | UniProt:Q6UXY1-2 BAIAP2L2 |
| _timestamp | 2024-11-03 20:09:01 |
| chain | chain:1-529 |
| checksum | A9D16724F6FCE118 |
| comment | FUNCTION Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity).SUBCELLULAR LOCATION Localizes to RAB13-positive vesicles and to the plasma membrane at intercellular contacts.ALTERNATIVE PRODUCTS Expressed in the epithelial layer of the intestine (at protein level).DOMAIN The IMD domain consisting of an antiparallel dimer of three-helix bundles, featuring on one side a positively charged. The N-terminal alpha-helix inserts into the lipid bilayer. Also forms homodimers and homooligomers. The residue Trp-141 is essential for oligomer formation (By similarity). |
| created | [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 |
| description | recommendedName: fullName evidence="9"BAR/IMD domain-containing adapter protein 2-like 2 alternativeName: Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 shortName: BAI1-associated protein 2-like protein 2 alternativeName: Planar intestinal- and kidney-specific BAR domain protein shortName: Pinkbar |
| geneName | BAIAP2L2 UNQ9336/PRO34007 |
| identifier | Q6UXY1 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Cell junction Cell membrane Cytoplasmic vesicle Lipid-binding Membrane Phosphoprotein Proteomics identification Reference proteome SH3 domain |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | BAIAP2L2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8988846] ENSEMBL:ENSG00000128298 BAIAP2L2 [Homo sapiens] |
| secondaryIdentifier | BI2L2_HUMAN B0QYE2 Q96BG7 |
| sequenceLength | 529 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | Q6UXY1-2 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q6UXY1-2 BAIAP2L2 (220110)
