Query author contributions in Reactome
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Details on Person Adam10 knockout mice have impaired development of the margin...
| Class:Id | Summation:2193074 |
|---|---|
| _displayName | Adam10 knockout mice have impaired development of the margin... |
| _timestamp | 2013-05-15 14:32:26 |
| created | [InstanceEdit:2193073] Orlic-Milacic, M, 2012-04-11 |
| modified | [InstanceEdit:2978083] Orlic-Milacic, M, 2013-01-10 [InstanceEdit:3446777] Orlic-Milacic, M, 2013-05-15 |
| text | Adam10 knockout mice have impaired development of the marginal zone B-cell lineage, known to be dependent on Notch2 signaling. Notch2 activation is also impaired in Adam10 knockout mice, supporting the role of Adam10 in Notch2 proteolytic processing and activation upon ligand binding (Gibb et al. 2010). |
| (summation) | [Reaction:2193065] Adam10 cleaves Notch2 [Mus musculus] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Adam10 knockout mice have impaired development of the margin... (2193074)
