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Query author contributions in Reactome

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Details on Person Adam10 cleaves Notch2

Class:IdReaction:2193065
_displayNameAdam10 cleaves Notch2
_doReleaseTRUE
_timestamp2013-05-15 21:15:39
authored[InstanceEdit:2193076] Orlic-Milacic, M, 2012-04-11
catalystActivity[CatalystActivity:208925] metalloendopeptidase activity of Adam10 [plasma membrane]
compartment[Compartment:876] plasma membrane
created[InstanceEdit:2193066] Orlic-Milacic, M, 2012-04-11
edited[InstanceEdit:2267361] Matthews, L, 2012-05-24
[InstanceEdit:2272657] D'Eustachio, P, 2012-05-25
entityOnOtherCell[EntityWithAccessionedSequence:2032251] Dll1 [plasma membrane] [Mus musculus]
input[Complex:2032305] Dll1:Notch2 [plasma membrane] [Mus musculus]
isChimericFALSE
literatureReference[LiteratureReference:2172161] ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo
modified[InstanceEdit:2193076] Orlic-Milacic, M, 2012-04-11
[InstanceEdit:2197565] Orlic-Milacic, M, 2012-04-12
[InstanceEdit:2272810] Orlic-Milacic, M, 2012-05-25
[InstanceEdit:2457764] Orlic-Milacic, M, 2012-08-28
[InstanceEdit:3448658] Orlic-Milacic, M, 2013-05-15
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameAdam10 cleaves Notch2
output[Complex:2193072] Dll1:Notch2 fragment [plasma membrane] [Mus musculus]
releaseDate2012-06-12
reviewed[InstanceEdit:2272809] Haw, R, 2012-05-25
[InstanceEdit:3448657] Boyle, Scott, 2013-04-25
[InstanceEdit:3448655] Ilagan, Ma Xenia, 2013-04-25
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:2295272] R-MMU-2193065.2
summation[Summation:2193074] Adam10 knockout mice have impaired development of the margin...
(inferredFrom)[Reaction:157629] NOTCH2-ligand complex is cleaved to produce NEXT2 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9787410] Update Tracker - [Reaction:2193065] Adam10 cleaves Notch2 - v45:[modifyText]
[_UpdateTracker:9788080] Update Tracker - [Reaction:2193065] Adam10 cleaves Notch2 - v44:[modifyText]
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No pathways have been reviewed or authored by Adam10 cleaves Notch2 (2193065)